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Updated: Jun 13, 2026

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
08:42

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model

Published on: July 3, 2020

溶解体病理和骨质疏松症在失去H+驱动的溶解体Cl-积累后发生

Stefanie Weinert1, Sabrina Jabs, Chayarop Supanchart

  • 1Leibniz-Institut für Molekulare Pharmakologie (FMP), 13125 Berlin, Germany.

Science (New York, N.Y.)
|May 1, 2010
PubMed
概括

化物通道ClC-7 化物通道ClC-7

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Characterization of Neuronal Lysosome Interactome with Proximity Labeling Proteomics

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Lysosomes are membrane-enclosed spherical sacs derived from the Golgi apparatus. The most important function of the lysosome is degrading macromolecules and biological polymers that are released during membrane trafficking events such as the secretory, endocytic, autophagic, and phagocytic pathways. The degradation is carried out by several hydrolytic enzymes active in an acidic environment of the lysosomal lumen. These acid hydrolases are involved in cellular processes such as cell signaling,...
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