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Updated: Jun 13, 2026

Mapping Alzheimer's Disease Variants to Their Target Genes Using Computational Analysis of Chromatin Configuration
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Published on: January 9, 2020

对与阿尔茨海默氏症相关的遗传局部进行全基因组分析

Sudha Seshadri1, Annette L Fitzpatrick, M Arfan Ikram

  • 1Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.

JAMA
|May 13, 2010
PubMed
概括

这项研究确定了两个新的基因位置,BIN1和EXOC3L2 / BLOC1S3 / MARK4,与阿尔茨海默病 (AD) 风险有显著关联. 虽然得到证实,但这些和其他基因并没有改善AD预测模型.

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