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Updated: Oct 2, 2026

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice
06:32

Protective Efficacy and Pulmonary Immune Response Following Subcutaneous and Intranasal BCG Administration in Mice

Published on: September 19, 2016

对活体重组BCG-HIV疫苗的幽默和细胞介导免疫反应

A Aldovini1, R A Young

  • 1Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142.

Nature
|June 6, 1991
PubMed
概括

这项研究表明,结核疫苗Mycobacterium bovis bacillus Calmette-Guerin (BCG) 可以通过基因改造来表达外来蛋白质,例如来自HIV-1的蛋白质. 这些修改后的BCG疫苗可以有效触发免疫反应,为新疫苗开发铺平道路.

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Enrichment of Native and Recombinant Extracellular Vesicles of Mycobacteria06:38

Enrichment of Native and Recombinant Extracellular Vesicles of Mycobacteria

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