视觉皮层的潜力可以开发出对体感皮层独特的一系列功能单元
1Molecular Neurobiology Laboratory, Salk Institute, La Jolla, CA 92037.
概括
新皮层发育显示了可塑性. 移植的胚胎视觉皮层开发了体感"桶",表明大脑区域之间的差异化潜力类似.
科学领域:
- 神经科学是一个神经科学.
- 发展生物学 发展生物学
- 神经解剖学是一个神经解剖学.
背景情况:
- 哺乳动物新皮质中的特殊区域,如视觉皮质和体感皮质,以独特的建筑和功能特征来定义.
- 了解这些独特的特征是预先决定的还是受到表观遗传相互作用的影响,对于理解新皮层发育至关重要.
研究的目的:
- 通过检查一个区域的特征是否可以在另一个区域中出现来调查新皮层区域的发展潜力.
- 为了确定特定的新皮层区域特征在何种程度上是预先规定的或表观遗传决定的.
主要方法:
- 将晚期胚胎视觉皮层移植到老鼠的新生儿体感皮层.
- 移植组织的组织学和分子分析,以确定"桶"和相关的糖合物边界.
主要成果:
- 移植的视觉皮层成功地开发了"桶"及其特有的糖结酸边界.
- 这些结构形成了一个有组织的阵列,模仿了在本地体感皮质的桶场中观察到的模式.
结论:
- 发展中的新皮层区域具有相似的潜潜潜力,用于区分不同皮层区域的特征特征.
- 表观遗传因素和局部环境在塑造新皮质的功能组织方面发挥着重要作用,而不是仅仅是严格的遗传预定.
相关概念视频
Vision
Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
Somatosensation
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
Motor and Sensory Areas of the Cortex
The cerebral cortex, the brain's outermost layer, is pivotal in processing complex cognitive tasks, emotions, and various sensory inputs and executing voluntary motor activities. This intricate structure is divided into three primary functional areas: the motor areas, sensory areas, and association areas.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Motor Areas
The motor areas located in the frontal lobe are central to controlling voluntary movements. This region is further subdivided into the primary motor cortex and the premotor cortex.
Association Areas of the Cortex
Association areas are regions of the cerebral cortex that do not have a specific sensory or motor function. Instead, they integrate and interpret information from various sources to enable higher cognitive processes such as memory, learning, and decision-making. Some key association areas include the following:
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Prefrontal Association Area: This area is located in the frontal lobe and is involved in planning, decision-making, and moderating social behavior. It connects with primary motor areas,...
Sensory Perception: Organization of the Somatosensory System
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the stimulus...
Somatosensory, Motor, and Association Cortex
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at the...


