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素素和ATF3在状皮肤癌中的对立作用

Xunwei Wu1, Bach-Cuc Nguyen, Piotr Dziunycz

  • 1Cutaneous Biology Research Center, Massachusetts General Hospital, Charlestown, MA 02129, USA.

Nature
|May 21, 2010
PubMed
概括

氨酸抑制剂增加了状细胞癌 (SCC) 的风险. 抑制氨酸/NFAT信号促进皮肤瘤的形成,通过抑制p53-依赖的衰老,ATF3发挥关键作用.

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