自闭症儿童的父母介导的以沟通为中心的治疗 (PACT):一种随机对照试验
Jonathan Green1, Tony Charman, Helen McConachie
1Psychiatry Research Group, University of Manchester, Manchester, UK. jonathan.green@manchester.ac.uk
Lancet (London, England)
|May 25, 2010
概括
学前自闭症沟通试验 (PACT) 没有显著降低幼儿自闭症症状严重程度. 然而,PACT在改善亲子社会沟通方面显示出好处,这表明早期自闭症干预的有针对性的优势.
科学领域:
- 发展心理学 发展心理学
- 临床心理学 临床心理学
- 儿科 儿科 儿科
背景情况:
- 小规模试验表明,早期的社会沟通干预措施对儿童自闭症有效.
- 这项较大的试验调查了儿童自闭症的家长介导干预的疗效.
研究的目的:
- 为了评估学前自闭症沟通试验 (PACT) 干预措施与通常治疗相比的有效性.
- 评估PACT对自闭症症状严重程度,亲子互动,儿童语言和适应性功能的影响.
主要方法:
- 随机对照试验涉及152名2至4岁,11个月的核心自闭症儿童.
- 儿童被分配到PACT干预加上通常的治疗,或单独接受通常的治疗.
- 主要结局是自闭症症状严重程度,通过13个月的自闭症诊断观察时间表-通用 (ADOS-G) 测量.
主要成果:
- 在PACT组和通常治疗组之间,自闭症症状严重程度 (ADOS-G评分) 没有显著差异.
- PACT干预措施对亲子互动产生了积极影响,包括父母同步反应和儿童启动.
- 在父母和孩子的共同注意力方面,有所改善,而对语言和适应性功能的影响是最小的.
结论:
- 将PACT干预添加到标准治疗中并没有导致整体自闭症症状的显著减少.
- 观察到,PACT的显著好处在于增强双向的亲子社会沟通技巧.
- 研究结果表明,PACT可能对自闭症幼儿的社会沟通的特定方面有好处.
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