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Identification of RNAs Engaged in Direct RNA-RNA Interaction with a Long Non-Coding RNA
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针对小沉默RNA的目标RNA指导的修剪和尾巴

Stefan L Ameres1, Michael D Horwich, Jui-Hung Hung

  • 1Howard Hughes Medical Institute and Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.

Science (New York, N.Y.)
|June 19, 2010
PubMed
概括

微RNAs (miRNAs) 和目标信使RNAs (mRNAs) 之间广泛的互补性触发了Drosophila中的miRNA尾巴和修剪. 这个过程被2-O-甲基化阻断,这解释了动物miRNA调节中的部分互补性.

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