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Updated: Jun 12, 2026

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells
14:02

Optimizing the Genetic Incorporation of Chemical Probes into GPCRs for Photo-crosslinking Mapping and Bioorthogonal Chemistry in Live Mammalian Cells

Published on: April 9, 2018

在活细胞表面使用合成探针对标签融合的GPCR蛋白进行选择性共价标记,用于其功能分析

Hiroshi Nonaka1, Sho-hei Fujishima, Sho-hei Uchinomiya

  • 1Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Katsura Campus, Nishikyo-ku, Kyoto 615-8510, Japan.

Journal of the American Chemical Society
|June 24, 2010
PubMed
概括

研究人员开发了一种用于细胞表面的G蛋白合受体 (GPCRs) 的新型共价标记方法. 这种技术使用标签和功能化分子探针来快速,选择性地标记和可视化活细胞中的蛋白质.

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