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在Morpholino-DNA表面杂交中的分子机制

Ping Gong1, Kang Wang, Yatao Liu

  • 1Seventh Sense Biosystems Inc., 101 Binney Street, Cambridge, Massachusetts 02142, USA.

Journal of the American Chemical Society
|June 25, 2010
PubMed
概括

莫尔福利诺斯 (MOs),无电荷核酸模仿,在表面杂交中比DNA具有明显的优势. MO-DNA相互作用对离子强度和表面拥挤不那么敏感,改善了诊断信号检测.

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