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Updated: May 9, 2026

Analysis of SCAP N-glycosylation and Trafficking in Human Cells
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Published on: November 8, 2016

斯芬戈辛-1-酸盐是E3泛基素结合酶TRAF2的缺失辅因子

Sergio E Alvarez1, Kuzhuvelil B Harikumar, Nitai C Hait

  • 1Department of Biochemistry and Molecular Biology and the Massey Cancer Center, Virginia Commonwealth University School of Medicine, 1101 E. Marshall Street, Richmond, Virginia 23298, USA.

Nature
|June 26, 2010
PubMed
概括

斯芬哥辛-1-酸盐 (S1P) 作为TRAF2的辅因子,TNF-α信号传递中的关键酶. 这一发现揭示了调节NF-kappaB激活的新机制,这对炎症和免疫至关重要.

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