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Updated: Jun 12, 2026

Interactions with and Membrane Permeabilization of Brain Mitochondria by Amyloid Fibrils
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在体外由α-synuclein形成的粉样蛋白主要是由疏水界面的反应主导的

Jeremy Pronchik1, Xianglan He, Jason T Giurleo

  • 1Department of Chemistry and Chemical Biology, Wright-Rieman Laboratories, Rutgers, the State University of New Jersey, New Brunswick, 610 Taylor Road, Piscataway, New Jersey 08854, USA.

Journal of the American Chemical Society
|June 29, 2010
PubMed
概括

刺激加速alpha-Synuclein (alphaSyn) 氨基代,主要是通过疏水-水接口反应,而不是质量转移或碎片化. 这一发现需要重新解释影响alphaSyn聚合倾向的因素.

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