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Updated: Jun 11, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

在Rh (I) 催化 (5 + 2) 循环添加中区域选择性的电子和固体控制:实验和理论

Peng Liu1, Lauren E Sirois, Paul Ha-Yeon Cheong

  • 1Department of Chemistry and Biochemistry, University of California, Los Angeles, California 90095-1569, USA.

Journal of the American Chemical Society
|July 1, 2010
PubMed
概括

乙烯基cyclopropanes (VCPs) 和alkynes之间的Rh(I) 催化 (5 + 2) 循环添加显示出基于替代物位置的可预测的区域选择性. 过渡状态中的绝缘和电子效应决定了这些重要的有机反应的结果.

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