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Updated: Jun 11, 2026

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae
15:12

Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein Expressed in Saccharomyces cerevisiae

Published on: May 10, 2014

外围蛋白质质量控制从血膜中去除未折叠的CFTR

Tsukasa Okiyoneda1, Hervé Barrière, Miklós Bagdány

  • 1Department of Physiology, and Groupe de Recherche Axé sur la Structure des Protéine (GRASP) McGill University, Montreal, Quebec H3G 1Y6, Canada.

Science (New York, N.Y.)
|July 3, 2010
PubMed
概括

研究人员确定了一个外围蛋白质质量控制系统,该系统在细胞表面降解未折叠的囊性纤维化转膜导电调节器 (CFTR). 这一过程涉及到无处不在,针对错误折叠的CFTR进行 lysosomal 降解,影响囊性纤维化治疗策略.

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Expression and Purification of the Cystic Fibrosis Transmembrane Conductance Regulator Protein in Saccharomyces cerevisiae14:56

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