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Updated: Jun 11, 2026

DNAzyme-dependent Analysis of rRNA 2’-O-Methylation
09:12

DNAzyme-dependent Analysis of rRNA 2’-O-Methylation

Published on: September 16, 2019

选择性2'-基乙化分析通过对外核糖酶的保护进行分析

Kady-Ann Steen1, Arun Malhotra, Kevin M Weeks

  • 1Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599-3290, USA.

Journal of the American Chemical Society
|July 6, 2010
PubMed
概括

一种新的RNase检测的SHAPE方法通过直接量化添加物来准确地绘制RNA结构,克服了RNA结构分析传统原始扩展方法的局限性.

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Protocol for the Solid-phase Synthesis of Oligomers of RNA Containing a 2'-O-thiophenylmethyl Modification and Characterization via Circular Dichroism

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