翻转MLL1的开关一个proline在一个时间
Edward J Grow1, Joanna Wysocka
1Department of Genetics, Stanford University, Stanford, CA 94305, USA.
Cell
|July 7, 2010
概括
混合血统白血病1 (MLL1) 蛋白调节血液发育中的Hox基因. 一种叫做cyclophilin CyP33的蛋白质可以切换MLL1.
科学领域:
- 分子生物学分子生物学
- 血液形成 血液形成 血液形成
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
背景情况:
- 混合血统白血病1 (MLL1) 蛋白质在血液形成过程中调节霍克斯基因表达起着至关重要的作用.
- 在各种形式的白血病中经常观察到MLL1的干扰.
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