是时候让瘤学家选择进行常规的退出HIV检测了吗?
Elizabeth Y Chiao1, Bruce J Dezube, Susan E Krown
1Department of Medicine, Baylor College of Medicine, and Health Services Research and Development, Department of Veterans Affairs Medical Center, Houston, Texas 77030, USA. echiao@bcm.edu
JAMA
|July 20, 2010
概括
建议对癌症患者进行常规选择退出的人类免疫缺陷病毒 (HIV) 测试. 这种方法可以通过在诊断出癌症的人的癌症治疗期间及时进行艾滋病毒管理来改善结果.
科学领域:
- 在瘤学瘤学.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 患有人类免疫缺陷病毒 (HIV) 的人患恶性瘤的风险增加.
- 常规的艾滋病毒检测不是癌症患者的标准护理,尽管CDC建议在所有医疗机构进行选择退出查.
- 目前的选择性艾滋病毒检测主要针对特定人群,在瘤学等更广泛的临床环境中实施有限.
研究的目的:
- 为癌症患者提供支持常规选择退出HIV检测的理由和证据.
- 讨论选择退出艾滋病毒检测的潜力,通过改善癌症治疗期间的艾滋病毒管理来提高临床结果.
主要方法:
- 对癌症患者选择退出HIV检测的背景,理由和支持证据的审查.
- 通过促进艾滋病毒管理来改善临床结果的证据的讨论.
主要成果:
- 受人类免疫缺陷病毒 (HIV) 感染的个体有患恶性瘤的高风险.
- 尽管有建议,但美国并没有广泛实施例行选择退出HIV测试.
- 选择退出测试在特定环境中显示出潜力,但需要更广泛的应用.
结论:
- 常规的选择性艾滋病毒检测应该被认为是癌症患者的标准护理.
- 实施选择退出艾滋病毒检测可以在癌症治疗期间更好地管理艾滋病毒.
- 这一策略有可能显著改善艾滋病毒阳性癌症患者的临床结果.
相关概念视频
Cancer Vaccines
Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Treatment Resistent Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Treatment Resistant Cancers
Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Cancer Prevention
Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
Some...
Some...
Cancer Therapies
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...

