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相关概念视频

Mitosis and Cytokinesis02:03

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
Mitosis and Cytokinesis02:03

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...
Mitosis and Cytokinesis01:35

Mitosis and Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...
Determining the Plane of Cell Division02:13

Determining the Plane of Cell Division

Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
Animal cells
In animal cells, the cleavage furrow forms along the plane of cell division starting...
Mitosis And Cytokinesis01:35

Mitosis And Cytokinesis

In eukaryotes, the cell division cycle is divided into distinct, coordinated cellular processes that include cell growth, DNA replication/chromosome duplication, chromosome distribution to daughter cells, and finally, cell division. The cell cycle is tightly regulated by its regulatory systems as well as extracellular signals that affect cell proliferation.
The processes of the cell cycle occur over approximately 24 hours (in typical human cells) and in two major distinguishable stages. The...

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相关实验视频

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Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells
15:41

Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells

Published on: December 3, 2010

细胞分裂与细胞几何学相交.

James B Moseley1, Paul Nurse

  • 1The Rockefeller University, New York, NY 10065, USA. jmoseley@rockefeller.edu

Cell
|July 27, 2010
PubMed
概括

单细胞生物感知细胞形状,以调节细胞分裂时间和染色体分离. 这种几何感应将细胞分裂控制与确保适当的DNA分布联系起来.

科学领域:

  • 细胞生物学 细胞生物学
  • 微生物学 微生物学
  • 遗传学 是一个遗传学.

背景情况:

  • 单细胞生物拥有复杂的机制来监控其物理环境.
  • 细胞几何在调节基本的细胞过程中起着至关重要的作用,如分裂.

研究的目的:

  • 研究单细胞生物如何利用细胞几何信息.
  • 了解几何感知与细胞分裂和染色体分离的控制之间的联系.

主要方法:

  • 对单细胞生物的观测研究.
  • 细胞几何传感路径的分析.
  • 研究细胞分裂控制与染色体分离机制之间的联系.

主要成果:

  • 单细胞生物积极监测细胞几何.
  • 几何感应机制影响细胞分裂的启动和染色体分离的方向.
  • 控制细胞分裂的信号与确保精确染色体分离的信号之间存在潜在的联系.

结论:

  • 细胞几何是单细胞生物细胞分裂调节的一个关键因素.
  • 几何传感与染色体分离过程相结合.

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Improved Visualization and Quantitative Analysis of Drug Effects Using Micropatterned Cells
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Published on: December 3, 2010

Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage
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Visualization of Chondrocyte Intercalation and Directional Proliferation via Zebrabow Clonal Cell Analysis in the Embryonic Meckel’s Cartilage

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Mammalian Cell Division in 3D Matrices via Quantitative Confocal Reflection Microscopy
10:22

Mammalian Cell Division in 3D Matrices via Quantitative Confocal Reflection Microscopy

Published on: November 29, 2017

  • 需要进一步的研究来阐明连接细胞几何与细胞分裂和分离的精确信号通路.