怀孕期热囊细胞疾病
Michael J Seckl1, Neil J Sebire, Ross S Berkowitz
1Department of Cancer Medicine, Charing Cross Gestational Trophoblastic Disease Centre, Charing Cross Hospital Campus of Imperial College London, London, UK. m.seckl@imperial.ac.uk
Lancet (London, England)
|August 3, 2010
概括
孕期热囊细胞疾病 (GTD) 管理已取得显著进展,在恶性形式中实现了超过98%的治愈率. 有效的治疗方法,生物标志物使用和集中护理已经大大改善了这些罕见瘤的女性的治疗结果.
科学领域:
- 妇科 妇科医生 妇科
- 在瘤学瘤学.
- 生殖医学 生殖医学
背景情况:
- 孕期热原体疾病 (GTD) 包括前恶性水性形和恶性GT瘤,如胆管癌.
- 从历史上看,恶性GTD的死亡率很高.
研究的目的:
- 总结目前GTD的管理策略.
- 讨论关于GTD的争议和未来研究.
主要方法:
- 对GTD的管理和后续协议的审查.
- 分析有助于改善治愈率的因素.
主要成果:
- 目前的管理协议实现了超过98%的GTD治愈率.
- 有效的治疗方法,作为生物标志物的人类胆性腺激素 (hCG),以及集中治疗是成功的关键.
结论:
- 现代管理已经改变了GTD的结果,使得高治愈率和生育能力得到保护.
- 持续的研究和集中护理对于进一步的进步至关重要.
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