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Updated: May 16, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

一个由p53诱导的大型基因间非编码RNA在p53反应中调解了全球基因抑制

Maite Huarte1, Mitchell Guttman, David Feldser

  • 1The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. mhuarte@broadinstitute.org

Cell
|August 3, 2010
PubMed
概括

研究人员确定了由p53.3调节的大型跨基因非编码RNA (lincRNAs). 一个lincRNA,lincRNA-p21,作为抑制剂,与hNRNP-K相互作用,控制基因表达和亡.

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