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Updated: Jun 10, 2026

Efficient Synthesis of All-Carbon Quaternary Centers via the Conjugate Addition of Functionalized Monoorganozinc Bromides
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1,4,7-Trimethyloxatriquinane: S(N) 2 在三级碳的反应

Mark Mascal1, Nema Hafezi, Michael D Toney

  • 1Department of Chemistry, University of California Davis, 1 Shields Avenue, Davis, California 95616, USA. mascal@chem.ucdavis.edu

Journal of the American Chemical Society
|August 5, 2010
PubMed
概括

1,4,7-trimethyloxatriquinane,一种三级基氧盐,抵抗酒解,但通过S(N) 2替代与化物反应. 这种三级碳替代挑战了典型的反应模式,得到了动力学和建模的支持.

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