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Updated: Jun 10, 2026

Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine
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Enzymatic Cascade Reactions for the Synthesis of Chiral Amino Alcohols from L-lysine

Published on: February 16, 2018

结构上有信息的立体化学无序阿尔多酶的位点导向突变发生,以提供立体化学互补的生物催化剂

Sylvain F Royer1, Luke Haslett, Susan J Crennell

  • 1Centre for Extremophile Research, Department of Biology and Biochemistry, University of Bath, Bath, United Kingdom BA2 7AY.

Journal of the American Chemical Society
|August 6, 2010
PubMed
概括

研究人员从Sulfolobus solfataricus中设计了一种热稳定的阿尔多酶,以改善碳-碳键形成的立体化学控制. 这项工作增强了特定的D-2-keto-3-deoxygluconate (D-KDGlu) 和D-2-keto-3-deoxy-galactonate (D-KDGal) 异构体的产生.

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