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来自Bacillus cereusus的皮酸环化前体的基因拦截和结构特征

Albert A Bowers1, Christopher T Walsh, Michael G Acker

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Journal of the American Chemical Society
|August 17, 2010
PubMed
概括

研究人员确定了TclM酶,该酶负责形成硫素抗生素中的氨酸核. 破坏tclM允许隔离非循环前体,证实了tclM的存在.

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