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关于EGFR不对称的内在和外在

Daniel J Leahy1

  • 1Department of Biophysics & Biophysical Chemistry, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA. dleahy@jhmi.edu

Cell
|August 21, 2010
PubMed
概括

一项新的研究揭示了Drosophila表皮生长因子受体 (EGFR) 形成了一个不对称的二元体,与连接体结合到一个子单元. 这一发现解释了负面的合作性,并影响了人类EGFR激活模型.

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