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一种Vibrio效应蛋白是一种内醇酸酶,破坏宿主细胞膜完整性

Christopher A Broberg1, Lingling Zhang, Herman Gonzalez

  • 1Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|August 21, 2010
PubMed
概括

维布里奥帕拉海莫利蒂克斯 (Vibrio parahaemolyticus) 使用效应器VPA0450破坏人类细胞膜,导致细胞死亡. 这种细菌蛋白质改变了内醇信号传递,影响了膜完整性和宿主细胞功能.

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