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Updated: Jun 9, 2026

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation
09:16

Exogenous Administration of Microsomes-associated Alpha-synuclein Aggregates to Primary Neurons As a Powerful Cell Model of Fibrils Formation

Published on: June 26, 2018

在体内和体外,α-synuclein促进SNARE复合体的组合

Jacqueline Burré1, Manu Sharma, Theodoros Tsetsenis

  • 1Department of Molecular and Cellular Physiology, and Howard Hughes Medical Institute, Stanford University, 1050 Arastradero Road, Palo Alto, CA 94304-5543, USA.

Science (New York, N.Y.)
|August 28, 2010
PubMed
概括

协核素,包括α-synuclein,作为伴侣,维持可溶性N-乙基胺敏感因子附着蛋白受体 (SNARE) 复合组合在神经终端. 同核素的损失导致老年依赖的神经系统衰退和小鼠的过早死亡.

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Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays09:36

Recombinant α- β- and γ-Synucleins Stimulate Protein Phosphatase 2A Catalytic Subunit Activity in Cell Free Assays

Published on: August 13, 2017

Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons10:03

Studying Pre-formed Fibril Induced α-Synuclein Accumulation in Primary Embryonic Mouse Midbrain Dopamine Neurons

Published on: August 16, 2020

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