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DNA pol λ 的非凡的能力是稳定不对齐的DNA

Meredith C Foley1, Victoria A Padow, Tamar Schlick

  • 1Department of Chemistry and Courant Institute of Mathematical Sciences, New York University, 251 Mercer Street, New York, New York 10012, USA.

Journal of the American Chemical Society
|September 9, 2010
PubMed
概括

由于有利的静电相互作用稳定了不对齐的DNA,DNA聚合酶兰巴 (pol λ) 导致的删除错误比聚合酶β (pol β) 更多. 在pol λ中的特定残留物,与pol β不同,创建一个稳定DNA错位的网络.

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