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Updated: Jun 8, 2026

Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells
08:32

Application of Genetically Encoded Fluorescent Nitric Oxide (NO•) Probes, the geNOps, for Real-time Imaging of NO• Signals in Single Cells

Published on: March 16, 2017

强效,高度选择性,口服生物可用,是神经神经氧化合成酶的化石化单基酶抑制剂

Fengtian Xue1, Huiying Li, Silvia L Delker

  • 1Department of Chemistry and Biochemistry, Center for Molecular Innovation and Drug Discovery, Chemistry of Life Processes Institute, Northwestern University, 2145 Sheridan Road, Evanston, Illinois 60208-3113, USA.

Journal of the American Chemical Society
|September 17, 2010
PubMed
概括

研究人员开发了强效和选择性的神经氧化合成酶 (nNOS) 抑制剂,改善了口服生物可用性. 新型二化化合物显示出增强的膜透性和针对性的结合,具有治疗潜力.

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