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Updated: May 2, 2026

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在控制Treg细胞介导的Th1反应调节中,miR-146a的功能

Li-Fan Lu1, Mark P Boldin, Ashutosh Chaudhry

  • 1Howard Hughes Medical Institute and Immunology Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10065, USA.

Cell
|September 21, 2010
PubMed
概括

微RNA-146a (miR-146a) 对于调节性T (Treg) 细胞功能至关重要,在维持免疫平衡中起着至关重要的作用. 它在Treg细胞中缺少,通过增加Stat1激活,突出miR-146a导致致命的炎症.

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