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Updated: Jun 8, 2026

The ChroP Approach Combines ChIP and Mass Spectrometry to Dissect Locus-specific Proteomic Landscapes of Chromatin
24:02

The ChroP Approach Combines ChIP and Mass Spectrometry to Dissect Locus-specific Proteomic Landscapes of Chromatin

Published on: April 11, 2014

定量相互作用蛋白质组学和表观基因组组标记及其读取器的全基因组概况

Michiel Vermeulen1, H Christian Eberl, Filomena Matarese

  • 1Department of Proteomics and Signal Transduction, Max-Planck-Institute of Biochemistry, D-82152 Martinsried, Germany. m.vermeulen-3@umcutrecht.nl

Cell
|September 21, 2010
PubMed
概括

基因组三甲基-氨酸标记是稳定的表观遗传调节剂. 这项研究确定了结合这些标记的特定蛋白质复合体,揭示了基因表达控制的机制.

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Adaptation of Hybridization Capture of Chromatin-associated Proteins for Proteomics to Mammalian Cells09:27

Adaptation of Hybridization Capture of Chromatin-associated Proteins for Proteomics to Mammalian Cells

Published on: June 1, 2018

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Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...