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Updated: Jun 8, 2026

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损伤诱导的Sld3酸化对于阻断晚期原始点火很重要

Jaime Lopez-Mosqueda1, Nancy L Maas, Zophonias O Jonsson

  • 1Department of Biochemistry and Biophysics, University of California, San Francisco, San Francisco, California 94158-9001, USA.

Nature
|September 25, 2010
PubMed
概括

在S相内部的检查点可以通过酸化Sld3和Dbf4.4来防止DNA损伤期间的晚期原始点火. 这通过控制DNA复制时间来确保基因组稳定性和细胞存活.

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