相关实验视频
医院内缺血性中风死亡率的风险评分在"了解指导方针-中风计划"中获得并验证
Eric E Smith1, Nandavar Shobha, David Dai
1Calgary Stroke Program, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada. eesmith@ucalgary.ca
Circulation
|September 30, 2010
概括
使用Get With the Guidelines-Stroke数据的新风险模型有助于预测缺血性中风后的住院死亡. 国家卫生研究院中风量表 (NIHSS) 评分是死亡率的强有力的预测指标.
科学领域:
- 神经学 神经学
- 心脏病学 心脏病学
- 公共卫生 公共卫生
背景情况:
- 在缺血性中风后预测住院死亡率的验证模型很少.
- 使用Get With the Guidelines-Stroke程序数据库来开发和验证这些模型.
研究的目的:
- 导出和验证在缺血性中风患者的住院死亡风险的预测模型.
- 评估国家卫生研究院中风量表 (NIHSS) 评分在死亡率预测中的有用性.
主要方法:
- 利用了来自"遵循指导方针-中风计划 (2001-2007) "的274,988名缺血性中风患者的数据.
- 使用后勤回归来识别死亡率的独立预测因素并创建预测模型.
- 在单独的样本中验证了该模型,特别是在记录NIHSS分数的患者中.
主要成果:
- 总体而言,住院死亡率为5.5%.
- 衍生的预测模型显示出良好的区别 (在整体验证样本中C统计值为0.72).
- 一个包含NIHSS得分的模型实现了更高的歧视 (C统计0.85),仅NIHSS就显示了强大的预测能力 (C统计0.83).
结论:
- 了解指南-中风风险模型是用于床边死亡风险分层的经过验证,实用的工具.
- NIHSS得分是一个至关重要的预测指标,显著提高了缺血性中风患者的短期死亡风险评估.
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