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Updated: May 5, 2026

Assessment of Immunologically Relevant Dynamic Tertiary Structural Features of the HIV-1 V3 Loop Crown R2 Sequence by ab initio Folding
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Published on: September 16, 2010

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多活性性通过异构结合增加了抗HIV抗体的明显亲和力

Hugo Mouquet1, Johannes F Scheid, Markus J Zoller

  • 1Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA.

Nature
|October 1, 2010
PubMed
概括

针对艾滋病毒的抗体通过突变获得了广度和强度. 令人惊的是,多活性抗体在HIV上结合多个部位,增强中和,尽管个体部位亲和度较低.

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