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Updated: Jun 8, 2026

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes

Published on: April 4, 2025

几种DNA聚合酶的活性位点上的多种分子相互作用:非极性核酸异构体作为探针

Juan C Morales1, Eric T Kool

  • 1Contribution from the Department of Chemistry, University of Rochester, Rochester, New York 14627.

Journal of the American Chemical Society
|October 1, 2010
PubMed
概括

这项研究探讨了DNA聚合酶和逆转录酶与非极性核糖类相似物F,Z和Q的相互作用. 不同的酶表现出不同的能力来复制这些不自然的基对,强调了小沟相互作用的重要性.

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