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Updated: Jun 8, 2026

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay
07:10

Conformational Evaluation of HIV-1 Trimeric Envelope Glycoproteins Using a Cell-based ELISA Assay

Published on: September 14, 2014

高亲和性甘聚合物与人类DC-SIGN结合,并破坏DC-SIGN与HIV包膜甘蛋白相互作用

C Remzi Becer1, Matthew I Gibson, Jin Geng

  • 1Department of Chemistry, University of Warwick, CV4 7AL Coventry, UK.

Journal of the American Chemical Society
|October 12, 2010
PubMed
概括

简单的甘油聚合物可以阻断人体树突细胞莱克 (DC-SIGN) 和HIV的gp120.之间的相互作用. 这一发现为艾滋病毒感染和潜在的治疗策略提供了新的见解.

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Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers11:45

Imaging of HIV-1 Envelope-induced Virological Synapse and Signaling on Synthetic Lipid Bilayers

Published on: March 8, 2012

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Inhibitors of Virion Maturation and Assembly01:19

Inhibitors of Virion Maturation and Assembly

As part of their replication cycle, certain viruses synthesize long precursor proteins called polyproteins within infected host cells. In human immunodeficiency virus (HIV), two major polyproteins are produced: Gag and Gag-Pol. The Gag polyprotein supplies the structural components of the virus, while Gag-Pol includes essential viral enzymes such as reverse transcriptase, integrase, and protease. After synthesis, these polyproteins move to the host cell membrane, where they assemble into an...