在冠状动脉旁路移植手术中使用输血的变化
Elliott Bennett-Guerrero1, Yue Zhao, Sean M O'Brien
1Division of Perioperative Clinical Research, Duke Clinical Research Institute, Duke University Medical Center, PO Box 3094, Durham, NC 27710, USA. elliott.bennettguerrero@duke.edu
JAMA
|October 14, 2010
概括
对于冠状动脉旁路移植 (CABG) 手术患者,红细胞 (RBC),血和血小板的医院输血率差异很大. 这种变化存在于患者因素之外,突出了实践标准化的潜在领域.
科学领域:
- 心血管外科心血管外科
- 输血医学 输血医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 在外科手术期间输血需要付出巨大的费用,并引发了安全问题.
- 减少输血使用的倡议正在进行中,但输血率在医院一级的变化仍未得到量化.
- 了解这种变化对于改善患者护理和资源配置至关重要.
研究的目的:
- 评估使用全源红细胞 (RBC),新鲜冷血和血小板输血的医院水平变化的程度.
- 调查导致冠状动脉旁路移植 (CABG) 手术的患者中这种变异的因素.
主要方法:
- 一项观察性队列研究包括102470名患者,他们在2008年在798家美国医院接受了初级隔离CABG手术.
- 数据来源于胸腔外科医生协会成人心脏手术数据库.
- 红细胞,新鲜冷血和血小板的术后输血是评估的主要结果.
主要成果:
- 输血率在各医院有显著差异:红细胞 (7.8%92.8%),新鲜冷血 (0%97.5%),血小板 (0.4%90.4%).
- 多变量分析表明,地理位置,学术地位和医院体积与输血率有关.
- 然而,这些因素,以及病例组合,只解释了红细胞使用中观察到的一部分变化.
结论:
- 美国各医院对CABG手术患者的红细胞和其他血液产品输血率存在显著的变化.
- 即使考虑到患者病例组合和确定的医院特征,这种变化仍然存在.
- 需要进一步的研究来确定这种变化的驱动因素,并实施标准化输血实践.
相关概念视频
Blood Transfusion and Agglutination
13.2K
Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
13.2K
Blood Transfusion
3.0K
Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
3.0K


