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Updated: May 2, 2026

Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking
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Monitoring the Assembly of a Secreted Bacterial Virulence Factor Using Site-specific Crosslinking

Published on: December 17, 2013

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细菌ECF载体S组件的结构和机制

Peng Zhang1, Jiawei Wang, Yigong Shi

  • 1Department of Molecular Biology, Lewis Thomas Laboratory, Princeton University, Princeton, New Jersey 08544, USA.

Nature
|October 26, 2010
PubMed
概括

研究人员确定了RIBU的结构,RIBU是能量合因子 (ECF) 载体中的关键蛋白质,揭示了其 рибофлавин结合部位和 prokaryotes 中必需维生素吸收的潜在运输机制.

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After budding out from the ER membrane, some COPII vesicles lose their coat and fuse with one another to form larger vesicles and interconnected tubules called vesicular tubular clusters or VTCs. These clusters constitute a compartment at the ER-Golgi interface known as ERGIC (Endoplasmic Reticulum Golgi Intermediate Compartment). The ERGIC is a mobile membrane-bound cargo transport system that sorts proteins secreted from ER and delivers them to the Golgi.
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