把我放在重复的重复上
Iestyn Whitehouse1, Tom Owen-Hughes
1Sloan-Kettering Institute, New York, NY 10065, USA.
Cell
|October 30, 2010
概括
在ATRX蛋白中发生的突变会导致阿尔法血症和精神障碍. ATRX通过结合富G重复来改变基因表达,沉默严重程度与重复数量相关.
科学领域:
- 遗传学和分子生物学
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
- 染色体重塑 染色体重塑 的方法
背景情况:
- 阿尔法血症和精神障碍与ATRX基因的突变有关.
- 与ATRX相关的疾病的严重程度并不取决于特定的突变.
- ATRX是一种染色体重塑蛋白,参与基因调节.
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