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通过抑制细菌酶来减轻癌症药物毒性

Bret D Wallace1, Hongwei Wang, Kimberly T Lane

  • 1Department of Chemistry, University of North Carolina, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|November 6, 2010
PubMed
概括

研究人员开发了针对导致严重腹的细菌酶的向抑制剂,由结肠癌药物CPT-11引起. 这些抑制剂保护肠道微生物,减少小鼠药物毒性,为癌症治疗提供了一种新的策略.

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