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Hand Dissection of Caenorhabditis elegans Intestines
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凯诺哈比蒂斯伊莱根斯3'UTRs的形成,调节和演变

Calvin H Jan1, Robin C Friedman, J Graham Ruby

  • 1Whitehead Institute for Biomedical Research, Cambridge, Massachusetts 02142, USA.

Nature
|November 19, 2010
PubMed
概括

研究人员通过测序 (3P-Seq) 开发了多A位置分析,以识别C. elegans中的信使RNA 3'未翻译区域 (UTR). 这种方法扩展了已知的UTR,揭示了对基因组紧缩和基因调节的见解.

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Cis-regulatory Sequences02:02

Cis-regulatory Sequences

Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...