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Updated: May 9, 2026

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
11:52

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level

Published on: April 23, 2016

神经元中的L1逆转换是由MeCP2调节的

Alysson R Muotri1, Maria C N Marchetto, Nicole G Coufal

  • 1University of California San Diego, School of Medicine, Department of Pediatrics/Rady Children's Hospital San Diego, La Jolla, California 92093-0695, USA. muotri@ucsd.edu

Nature
|November 19, 2010
PubMed
概括

长间隔的核元素-1 (LINE-1或L1s) 逆转移子在大脑中动员,特别是当甲基-CpG结合蛋白2 (MeCP2) 缺席时. 在雷特综合征中发现的MeCP2突变增加了L1逆转换易感性,影响神经系统疾病.

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