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子纤维细胞的生长抑制剂

R R Bürk1

  • 1Medical Research Council, Experimental Virus Research Unit, Institute of Virology, University of Glasgow.

Nature
|November 25, 2010
PubMed
概括

No abstract available in PubMed .

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Rudolph Virchow discovered spindle-shaped cells called fibroblasts in 1858. Inactive fibroblasts, called fibrocytes, become activated by various stimuli, such as growth factors and inflammatory cytokines. Activated fibroblasts play a crucial role in wound healing, inflammation, formation of new blood vessels, and cancer progression. Uncontrolled activation of fibroblasts results in fibrosis, the excess deposition of fibrous tissue, which can lead to scarring and affect normal organs. This...
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