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Updated: Jun 6, 2026

Yeast As a Chassis for Developing Functional Assays to Study Human P53
14:57

Yeast As a Chassis for Developing Functional Assays to Study Human P53

Published on: August 4, 2019

在高度瘤中选择性激活p53介导的瘤抑制

Melissa R Junttila1, Anthony N Karnezis, Daniel Garcia

  • 1University of California San Francisco, Department of Pathology and Helen Diller Family Comprehensive Cancer Center, San Francisco, California 94143-0502, USA.

Nature
|November 26, 2010
PubMed
概括

在非小细胞肺癌 (NSCLC) 的小鼠模型中恢复瘤抑制剂p53并没有缩小已建立的瘤. 然而,通过选择性向具有高Ras信号的侵袭性癌细胞,p53恢复可以减少高度瘤.

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