偏头痛和来自女性缺血性大脑事件的功能性结果
Pamela M Rist1, Julie E Buring, Carlos S Kase
1Division of Preventive Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass., USA.
Circulation
|December 4, 2010
概括
患有偏头痛与光环的女性面临过渡性缺血性发作 (TIA) 或缺血性中风的风险更高. 这种风险与这些脑血管事件后的良好功能结果有关.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 心血管科学 心血管科学
背景情况:
- 带有光环的偏头痛与女性缺血性中风风险增加有关.
- 关于偏头痛对缺血事件后功能结果的影响的数据有限.
研究的目的:
- 为了研究偏头痛类型和缺血性脑血管事件后的功能结果之间的关联.
- 分析偏头痛与诸如暂时性缺血性发作 (TIA) 和中风等结果之间的关系.
主要方法:
- 从妇女健康研究中对27,852名女性进行前性队列研究.
- 偏头痛分类为:没有病史,活跃有光环,活跃没有光环,过去的病史.
- 多项逻辑回归用于评估偏头痛与TIA/中风后的功能结果 (mRS分数) 的联系.
主要成果:
- 在13.5年的时间里,发生了398次TIA和345次缺血性中风.
- 偏头痛与光环相关的TIA风险为1.56,中风风险为2.33,具有良好的功能结果 (mRS 0-1).
- 没有显著的结果 偏头痛的风险增加 没有光环或过去的偏头痛史.
结论:
- 患有偏头痛与光环的女性患TIA或缺血性中风的风险较高.
- 增加的风险似乎特别与中风与有利的功能恢复有关.
相关概念视频
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