对复发性静脉血栓塞的风险评估
Paul Alexander Kyrle1, Frits R Rosendaal, Sabine Eichinger
1Department of Medicine I, Medical University of Vienna, Vienna, Austria. paul.kyrle@meduniwien.ac.at
Lancet (London, England)
|December 7, 2010
概括
预测复发性静脉血栓形成是具有挑战性的. 整合全球标志物和临床因素可以改善抗凝治疗的风险评估,平衡疗效与出血风险.
科学领域:
- 血液学 血液学 血液学
- 血管医学 血管医学
- 血栓形成研究研究
背景情况:
- 静脉血栓经常复发,需要使用抗凝药.
- 抗凝固药物治疗减少了复发,但增加了出血风险.
- 准确的风险评估对于平衡治疗益处和危害至关重要.
研究的目的:
- 评估目前用于预测静脉血栓复发的方法.
- 确定改善风险分层在静脉血栓症患者的策略.
主要方法:
- 审查已确定的临床和实验室复发风险因素.
- 评估个别实验室标记物的有用性.
- 探索全球标志物和综合风险因素分析.
主要成果:
- 个别的实验室标记只能为复发提供适度的预测值.
- 多种风险因素的综合影响仍然不清楚.
- 全球标志物和对前列血栓变化与临床因素的整合显示出有前途.
结论:
- 不建议对个别实验室标记物进行例行查.
- 全球标记提供了一个更全面的风险评估方法.
- 整合凝血变化和临床因素可以完善静脉血栓复发的预测.
相关概念视频
Venous Thrombosis III: Interprofessional Care
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Venous Thrombosis I: Introduction
Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis IV: Nursing Management
Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Pulmonary Embolism III: Nursing Management
A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...
Venous Return
The circulatory system plays a crucial role in ensuring the optimal functioning of the human body. One of its critical components is venous return - the process that completes the blood circulation cycle. This article will delve into the concept of venous return, how it works, and its significance to our health.
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system as it...
What is Venous Return?
Venous return refers to the rate at which blood flows back to the heart from the body's peripheral veins. It's an integral part of the circulatory system as it...
