Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

What are Lipids?01:38

What are Lipids?

182.3K
Overview
182.3K
Lipids as Anchors01:32

Lipids as Anchors

6.0K
In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
6.0K
Proteomics01:33

Proteomics

7.5K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.5K
Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

5.5K
Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin,...
5.5K
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

7.0K
Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...
7.0K

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

A lipidomics roadmap: from basic research to societal challenges.

Nature communications·2026
Same author

Targeting excessive cholesterol deposition alleviates secondary lymphoedema.

Nature·2026
Same author

Integrative plasma metabolomic profiling identifies distinct vascular and inflammatory signatures in hospital emergency department patients.

Clinica chimica acta; international journal of clinical chemistry·2025
Same author

Lipidomic Signatures of Insulin Resistance Identified From Hyperinsulinemic-Euglycemic Clamp Studies in Asian Men.

Diabetes·2025
Same author

Ultrafast Measurement of Circulating Ceramides in Human Cohorts.

Analytical chemistry·2025
Same author

Introduction of a lipidomics scoring system for data quality assessment.

Journal of lipid research·2025

相关实验视频

Updated: May 5, 2026

Shotgun Lipidomics of Rodent Tissues
11:46

Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

3.0K

脂管学:新的工具和应用.

Markus R Wenk1

  • 1National University of Singapore, Yong Loo Lin School of Medicine, Department of Biochemistry, Centre for Life Sciences, Singapore. markus_wenk@nuhs.edu.sg

Cell
|December 15, 2010
PubMed
概括

脂质组学揭示了脂质是活跃的生物参与者,而不仅仅是碳储存. 像质谱仪这样的先进技术是了解它们多样化的细胞作用的关键.

科学领域:

  • 生物化学 生物化学
  • 细胞生物学 细胞生物学
  • 分析化学 分析化学

背景情况:

  • 脂质传统上被认为是被动的碳储存分子.
  • 最近的研究强调了脂质在生物系统中的积极作用.
  • 脂管学领域正在迅速发展.

研究的目的:

  • 突出了解脂质的转变,从被动储存到活跃的生物参与者.
  • 强调推动脂管学领域的技术进步.
  • 强调新工具在阐明脂质功能方面的潜力.

主要方法:

  • 质谱仪用于脂质检测和表征.
  • 脂质分析的补充分析方法.
  • 在体内检测脂质及其生物合成酶.

主要成果:

  • 脂质被认为是细胞过程的动态和不可或缺的组成部分.
  • 技术创新正在使全面的脂质分析成为可能.
  • 新的方法方便研究脂质生物合成和功能.

结论:

  • 脂管学是一个变革性的领域,提供了对生物系统的新见解.

更多相关视频

Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
09:00

Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Published on: July 14, 2022

2.8K
Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling
07:12

Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling

Published on: August 23, 2024

2.5K

相关实验视频

Last Updated: May 5, 2026

Shotgun Lipidomics of Rodent Tissues
11:46

Shotgun Lipidomics of Rodent Tissues

Published on: November 18, 2022

3.0K
Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
09:00

Sample Preparation for Rapid Lipid Analysis in Drosophila Brain Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Published on: July 14, 2022

2.8K
Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling
07:12

Author Spotlight: Quantification of Complex Lipidomic Samples Using Stable Isotope Labeling

Published on: August 23, 2024

2.5K
  • 综合技术工具对于推进脂质研究至关重要.
  • 了解脂质对于理解各种生物功能至关重要.