发展中国家的流行性医疗相关感染负担:系统性审查和元分析
Benedetta Allegranzi1, Sepideh Bagheri Nejad, Christophe Combescure
1First Global Patient Safety Challenge, WHO Patient Safety, Geneva, Switzerland.
Lancet (London, England)
|December 15, 2010
概括
与医疗保健相关的感染在发展中国家是一个常见的问题,其患病率高于欧洲或美国. 改善感染控制和监测至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 与医疗保健相关的感染 (HAI) 是一个重大的全球挑战,主要影响患者安全.
- 发展中国家高血压感染流行病学的数据很少,这阻碍了有针对性的干预.
- 世界卫生组织强调,需要更好地了解资源有限的环境中HAI负担.
研究的目的:
- 系统地评估发展中国家流行性医疗保健相关感染的流行病学.
- 确定这些地区的HAI的流行,发病率和微生物原因.
- 为了比较发展中国家的HAI率与发达国家报告的HAI率.
主要方法:
- 在电子数据库和参考列表中对1995年至2008年间发表的研究进行了全面的文献搜索.
- 选择了来自发展中国家的研究,提供有关HAI流行或发病率的数据,包括特定的感染地点和致病因子.
- 评估了研究质量,并将数据聚合起来进行分析,重点是高质量的研究.
主要成果:
- 总共包括220项研究,显示许多发展中国家的数据代表性有限,其中54%被归类为低质量.
- 高质量的研究表明,与欧洲和美国相比,高质量感染的患病率明显高 (15.5%).
- 成人重症监护病房报告HAI密度 (47.9每1000病日) 至少是美国的三倍,手术部位感染是最常见的医院感染.
结论:
- 发展中国家面临着与医疗保健相关的感染的巨大负担.
- 迫切需要加强监测系统,并在这些地区实施强有力的感染控制实践.
- 这些发现强调了数据的关键差距和改善医疗保健标准的必要性,以减轻HAI风险.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies. Common...
Amebiasis
Entamoeba histolytica, a protozoan parasite, is responsible for intestinal and extraintestinal amebiasis. Though a significant proportion of infections remain asymptomatic, approximately 50 million individuals annually are estimated to present with clinical disease, resulting in up to 100,000 deaths globally. The disease burden is disproportionately high in regions with lower socioeconomic status, such as parts of India, Africa, Mexico, and Latin America.Etiology and TransmissionThe infective...
Factors Affecting the Risk of Infection
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin create...
Infection
When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
Methods Of Healthcare Delivery System
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is limited...
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is limited...


