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在由LTR逆转移子暂停的复制分叉时,CENP-B保持了基因组完整性

Mikel Zaratiegui1, Matthew W Vaughn, Danielle V Irvine

  • 1Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, New York 11724, USA.

Nature
|December 15, 2010
PubMed
概括

中心结合蛋白B (CENP-B) 通过LTR逆转移子促进DNA复制叉的进展. 由于复制分叉阻塞,CENP-B的损失导致基因组不稳定,突出显示了它在维持基因组稳定中的作用.

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