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Updated: Jun 6, 2026

Characterizing Mutational Load and Clonal Composition of Human Blood
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Characterizing Mutational Load and Clonal Composition of Human Blood

Published on: July 11, 2019

在白血病中,克隆结构和传播细胞的遗传变异

Kristina Anderson1, Christoph Lutz, Frederik W van Delft

  • 1Section of Haemato-Oncology, The Institute of Cancer Research, Sutton SM2 5NG, UK.

Nature
|December 17, 2010
PubMed
概括

这项研究调查了儿童急性淋巴细胞白血病,该研究揭示了癌症亚克隆内的复杂遗传进化. 癌症干细胞表现出多样化的遗传,影响白血病的传播,并为向治疗提供了洞察力.

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VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma

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