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Updated: Jun 5, 2026

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人类O-GlcNAc转移酶及其与基质复合物的结构

Michael B Lazarus1, Yunsun Nam, Jiaoyang Jiang

  • 1Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, USA.

Nature
|January 18, 2011
PubMed
概括

与O相关的β-N-乙糖胺转移酶 (OGT) 酶将新陈代谢与细胞信号连接起来. 结构研究揭示了OGT如何识别基质,有助于研究癌症和阿尔茨海默氏症等疾病.

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