聚合组体是基因沉默工厂吗?
Jacob W Hodgson1, Hugh W Brock
1Department of Zoology, University of British Columbia, Vancouver BC, Canada.
Cell
|January 19, 2011
概括
聚合组 (PcG) 蛋白质通过长距离的关联来帮助使霍克斯基因沉默. 这项研究表明,Hox基因位于核中的位置是PcG介导基因沉默的关键.
科学领域:
- 分子生物学分子生物学
- 遗传学 是一个遗传学.
- 表观遗传学 在表观遗传学中,表观遗传学是指表观遗传学.
背景情况:
- 多组 (PcG) 蛋白质是已知抑制基因表达的表观遗传调节剂.
- 霍克斯基因对发育至关重要,并且经常是PCG媒介抑制的目标.
- 长距离的染色体相互作用与基因调节有关.
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